Code
01CD5521
Duration
01 January 2022 → 30 September 2022
Funding
Regional and community funding: Special Research Fund
Promotor
Research disciplines
-
Medical and health sciences
- Radiation therapy
Keywords
Radiotherapy
Stem cells
Hematopoiesis
Proton therapy
Project description
The radiation response of hematopoietic stem and progenitor cells (HSPCs) to proton therapy is
unknown. In this project, the DNA damage response of radiosensitive HSPCs, which are often
exposed during pediatric cancer treatment, is compared between therapeutic proton- and photon
therapy. This study can improve proton treatment planning and can lead to new therapeutic interventions to prevent radiotherapy-related adverse effects.