Gnotobiotic Artemia brine shrimp as a model for studying the transcriptional, translational and epigenetic mechanisms responsible for immune 'imprinting' against infectious diseases in invertebrates

01 October 2015 → 30 September 2018
Regional and community funding: Special Research Fund
Research disciplines
  • Agricultural and food sciences
    • Aquaculture
    • Veterinary immunology
innate immunity innate immune memory
Project description

Invertebrates, including shrimps, rely on their innate immunity to fight against pathogens. Innate immunity lacks the ability to show high degree of specificity and long-lasting memory. However, few reports claimed that invertebrates show some form of immunological specificity and memory similar to that of adaptive immunity in vertebrates. Using the gnotobiotic brine shrimp Artemia as model organism, this project aims to unambiguously prove the possibility or impossibility of immune priming, examining the presence or absence of specific and enduring memory against homologous and heterologous antigens.