Research Explorer

Project

New Polymer-Protein Conjugation Methodology Based on Cationic Coupling Agents
Acronym
3PS00613
Code
3PGS00613W
Duration
01 October 2013 → 30 September 2014
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Engineering and technology
    • Catalysis and reacting systems engineering
    • Chemical product design and formulation
    • General chemical and biochemical engineering
    • Process engineering
    • Separation and membrane technologies
    • Transport phenomena
    • Other (bio)chemical engineering
    • Polymeric materials
Keywords
polymer protein conjugation therapeutics
 
Project description
 

Therapeutic biologicals are a growing part of the pharmaceutical market. The most important challenge for biologicals as therapeutics is to enhance plasma half-life, commonly achieved by modification with polymer chains. This increasing importance of polymer therapeutics creates the need for highly efficient coupling reactions. Within this project we envisage to develop via novel coupling strategy based on cationic coupling agents.