Project

Biochemical and molecular characterization of a new mitochondrial encoded target site for acaricides

Code

01J06307

Duration

01 January 2007 → 31 January 2010

Funding

Regional and community funding: Special Research Fund

Promotor

Luc Tirry

Research disciplines

Natural sciences
- Animal biology
- General biology
- Plant biology
Engineering and technology
- Biomaterials engineering
- Biological system engineering
- Biomaterials engineering
- Biomechanical engineering
- Other (bio)medical engineering
- Environmental engineering and biotechnology
- Industrial biotechnology
- Other biotechnology, bio-engineering and biosystem engineering
Agricultural and food sciences
- Agricultural plant production
- Horticultural production
- Veterinary medicine

Keywords

bifenazate Tetranychus urticae mode of action

Project description

Bifenazate is a recent, very effective and highly selective acaricide. The mode of action and the target site of this compound are unknown. Recently, it was found that the compound is triggering a new mitochondrial target site, after activation to an active metabolite. The purpose of the project is the elucidation of the target site and the activation pathway. These findings will open new perspectives for the control of the economically important spider mite, Tetranychus urticae.