Research Explorer

Project

Implementation of new tools to study the interaction between G protein-coupled receptors (GPCR dimers)
Code
01W02115
Duration
01 October 2015 → 30 September 2019
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Biochemistry and metabolism
    • Systems biology
  • Medical and health sciences
    • Medical biochemistry and metabolism
    • Medical biochemistry and metabolism
    • Medical biochemistry and metabolism
Keywords
dopamine receptor complementation assay resonance energy transfer assays (BRET/FRET) G protein-coupled receptors (GPCR) single cell microscopy dimer
 
Project description
 

In this project we will develop a screening technology based on complementation assays to study in detail the capacity of GPCRs to form dimers. This approach will give us the opportunity to study dimer localization via single cell microscopy.