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Project
The biology of tumor-derived extracellular RNA in liquid biopsies
Information
Project Team
Organisations
Outputs & Impact
Publications & research data ( 12 )
Blood collection tube and RNA purification method recommendations for extracellular RNA transcriptome profiling
The exRNAQC Consortium
Jasper Anckaert
Francisco Avila Cobos
Anneleen Decock
Philippe Decruyenaere
Jill Deleu
Katleen De Preter
Olivier De Wever
Jilke De Wilde
Bert Dhondt
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2025
Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies
Céleste Van Der Schueren
Philippe Decruyenaere
Francisco Avila Cobos
Johanna Bult
Jill Deleu
Lydia Dipalo
Hetty Helsmoortel
Eva Hulstaert
Annelien Morlion
Elena Ramos Varas
et al.
A1
Journal Article
in
MOLECULAR ONCOLOGY
2025
Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study
Anneleen Decock
Olivier De Wever
Celine Everaert
Hetty Helsmoortel
An Hendrix
Pieter Mestdagh
Annelien Morlion
Jo Vandesompele
Ruben Van Paemel
Francisco Avila Cobos
et al.
C3
Conference
2023
Reporting of pre-analytical variables in RNA-focused blood plasma studies : a prerequisite for quality assessment and replication
Céleste Van Der Schueren
Philippe Decruyenaere
Francisco Avila Cobos
Jill Deleu
Hetty Helsmoortel
Eva Hulstaert
Annelien Morlion
Kathleen Schoofs
Eveline Vanden Eynde
Kimberly Verniers
et al.
C3
Conference
2023
Dramatic impact of blood collection tube and RNA purification method on extracellular RNA transcriptomes
Jasper Anckaert
Francisco Avila Cobos
Anneleen Decock
Philippe Decruyenaere
Jill Deleu
Katleen De Preter
Olivier De Wever
Jilke De Wilde
Bert Dhondt
Thibaut D'huyvetter
et al.
C3
Conference
2023
Exploration of neuroblastoma xenograft models for tumor extracellular RNA profiling in murine blood plasma
Jill Deleu
Hanne Van Droogenbroeck
Jasper Anckaert
Anneleen Decock
Jilke De Wilde
Kaat Durinck
Liselot Mus
Justine Nuytens
Muhammad Rishfi
Kathleen Schoofs
et al.
A2
Journal Article
in
EXRNA
2023
Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study
Anneleen Decock
Olivier De Wever
Celine Everaert
Hetty Helsmoortel
An Hendrix
Pieter Mestdagh
Annelien Morlion
Jo Vandesompele
Ruben Van Paemel
Francisco Avila Cobos
et al.
C3
Conference
2023
Digital PCR-based evaluation of nucleic acid extraction kit performance for the co-purification of cell-free DNA and RNA
Jill Deleu
Kathleen Schoofs
Anneleen Decock
Kimberly Verniers
Sofie Roelandt
Angie Denolf
Joke Verreth
Bram De Wilde
Tom Van Maerken
Katleen De Preter
et al.
A1
Journal Article
in
HUMAN GENOMICS
2022
Whole transcriptome profiling of liquid biopsies from tumour xenografted mouse models enables specific monitoring of tumour-derived extracellular RNA
Vanessa Vermeirssen
Jill Deleu
Annelien Morlion
Celine Everaert
Jilke De Wilde
Jasper Anckaert
Kaat Durinck
Justine Nuytens
Muhammad Rishfi
Franki Speleman
et al.
A2
Journal Article
in
NAR CANCER
2022
mRNA capture sequencing and RT-qPCR for the detection of pathognomonic, novel, and secondary fusion transcripts in FFPE tissue : a sarcoma showcase
Anneleen Decock
David Creytens
Steve Lefever
Joni Van der Meulen
Jasper Anckaert
Ariane De Ganck
Jill Deleu
Bram De Wilde
Carolina Fierro
Scott Kuersten
et al.
A1
Journal Article
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2022
Substantial performance differences among RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study
Anneleen Decock
Olivier De Wever
Celine Everaert
Hetty Helsmoortel
An Hendrix
Pieter Mestdagh
Annelien Morlion
Jo Vandesompele
Ruben Van Paemel
Francisco Avila Cobos
et al.
C3
Conference
2021
Messenger RNA capture sequencing of extracellular RNA from human biofluids using a comprehensive set of spike-in controls
Eva Hulstaert
Anneleen Decock
Annelien Morlion
Celine Everaert
Kimberly Verniers
Justine Nuytens
Nele Nijs
Gary P. Schroth
Scott Kuersten
Stephen M. Gross
et al.
A2
Journal Article
in
STAR PROTOCOLS
2021
Activities ( 0 )
Results
Impact narratives ( 1 )
DNA and RNA
Area(s):
Health
Patents ( 0 )