Code
01D00124
Duration
01 October 2024 → 30 September 2028
Funding
Regional and community funding: Special Research Fund
Promotor
Research disciplines
-
Medical and health sciences
- Nutraceuticals
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Agricultural and food sciences
- Food sciences and (bio)technology not elsewhere classified
Keywords
Antidiabetic peptides
clam, molecular docking
peptide bioavailability
transport mechanisms
Project description
A comprehensive approach combining simulated gastrointestinal digestion (SGID) and in silico analysis will be used to facilitate the identification of antidiabetic peptide sequences derived from the manila clam. Conventional cell model and more experimental 3D intestinal organoid model will be applied for evaluating permeability of originated peptides and the mechanism involved in transmission through epithelial cells.