Project

Exploring the antidiabetic peptides from Manila clam (Ruditapes philippinarum): A comprehensive approach

Code

01D00124

Duration

01 October 2024 → 30 September 2028

Funding

Regional and community funding: Special Research Fund

Promotor

Mahta Mirzaei

Research disciplines

Medical and health sciences
- Nutraceuticals
Agricultural and food sciences
- Food sciences and (bio)technology not elsewhere classified

Keywords

Antidiabetic peptides clam, molecular docking peptide bioavailability transport mechanisms

Project description

A comprehensive approach combining simulated gastrointestinal digestion (SGID) and in silico analysis will be used to facilitate the identification of antidiabetic peptide sequences derived from the manila clam. Conventional cell model and more experimental 3D intestinal organoid model will be applied for evaluating permeability of originated peptides and the mechanism involved in transmission through epithelial cells.