Project

Development of electrochemical immunosensors for the detection of biomarkers

Code
bof/baf/4y/2024/01/217
Duration
01 January 2024 → 31 December 2025
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Chemical aspects of sensor technology
    • Electrochemical methods
  • Medical and health sciences
    • Protein diagnostics
Keywords
Electrochemical immunosensors Early disease detection Biomarker detection
 
Project description

This project focuses on developing electrochemical immunosensors for the early detection of diseases by identifying biomarkers. These sensors consist of a functionalized electrode array where immobilized matching antibodies specifically and selectively detect targeted protein biomarkers. Depending on the concentration of the targeted protein in the sample, varying amounts of biomarkers will bind to the antibodies, which can then be detected electrochemically. The focus is on a wide range of diseases, including cervical cancer and cardiovascular conditions, making the technology highly versatile. The basic research funding will be used for material research, prototyping, and validation in terms of sensitivity, selectivity, reproducibility, and stability over time, as well as preclinical tests.