Stroke is one of the leading causes of disability and mortality worldwide. The two main types of stroke are ischemic stroke (IS) and intracerebral hemorrhage (ICH). Epilepsy is a chronic neurological disease and is defined as the occurrence of epileptic seizures. Epileptic seizures are clinical manifestations resulting from excessive synchronous, abnormal firing patterns of neurons that are located predominantly in the cerebral cortex. Epileptic seizures are common following a stroke, but the underlying pathofysiology of post-stroke seizures is unknown. Using electrophysiological techniques combined with multimodal imaging and clincal data, my group is investigating the pathofysiology and associated factors of seizures following stroke in patients as well as in preclinical animal models.