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Project

tenure track appointment in paediatrics

Information

Project Team

Outputs and Outcomes

Publications

GTF3A mutations predispose to herpes simplex encephalitis by disrupting biogenesis of the host-derived RIG-I ligand RNA5SP141

Leslie NaesensSantoshi MuppalaDhiraj AcharyaJosephine NemegeerDelfien BogaertJung-Hyun LeeKatrien StaesVeronique DebackerPieter De BleserMarieke De BruyneElfride De BaereMichiel van GentGuanQun LiuBart LambrechtJens StaalTessa KerreRudi BeyaertJonathan MaelfaitSimon TavernierMichaela U. GackFilomeen Haerynck et al.

A1 Journal Article in SCIENCE IMMUNOLOGY

2022

Mutations in RNU7-1 weaken secondary RNA structure, induce MCP-1 and CXCL10 in CSF, and result in Aicardi-Goutières syndrome with severe end-organ involvement

Leslie NaesensJosephine NemegeerFilip RoelensLore VallaeysMarije MeuwissenKatrien JanssensPatrick VerlooBenson OgunjimiDimitri HemelsoetLevi HosteLisa RoelsMarieke De BruyneElfride De BaereJo Van DorpeAmélie DendoovenAnne SiebenGillian I. RiceTessa KerreRudi BeyaertCarolina UggentiYanick J. CrowSimon TavernierJonathan MaelfaitFilomeen Haerynck[missing] Program for Undiagnosed Rare Diseases (UD-PrOZA) et al.

A1 Journal Article in JOURNAL OF CLINICAL IMMUNOLOGY

2022