Implementation of Process Analytical Technology (PAT) systems in Pharmaceutical Production Processes

01 October 2008 → 30 September 2011
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Research disciplines
  • Medical and health sciences
    • Biomarker discovery and evaluation
    • Drug discovery and development
    • Medicinal products
    • Pharmaceutics
    • Pharmacognosy and phytochemistry
    • Pharmacology
    • Pharmacotherapy
    • Toxicology and toxinology
    • Other pharmaceutical sciences
pharmaceutical processes Process Analytical Technology (PAT) PAT tools
Project description

This project aims to develop a general strategy to implement and validate PAT systems in pharmaceutical production processes, allowing real-time release of the end product. Herewith, major attention is paid to the necessary use of complimentary PAT tools: in-line and real-time process analyzers (especially spectroscopic techniques), chemometrics, process control tools and knowledge management tools.