Project

Catalytic synthesis and ring opening of aziridines – novel protocols for the preparation of valuable nitrogen-containing target compounds

Duration
01 October 2010 → 30 September 2020
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Organic chemistry
Keywords
antimcrobials quinolines synthesis antimalarials
 
Project description

This project focuses on the synthesis of novel, biologically relevant quinoline derivatives. To that end, new synthetic strategies will be explored, such as catalytic hydroformylation and the synthesis and application of aziridine-quinoline hybrids. The new compounds will be tested for their bioactivities, especially concerning their antimalarial and antimicrobial activity.