Project

Redox-dependent regulation of Class II polyA-binding proteins

Code
01CD3823
Duration
01 October 2023 → 30 April 2024
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Proteins
    • Molecular and cell biology not elsewhere classified
    • Transcriptomics
Keywords
polyA-binding proteins oxidative stress plants
 
Project description

In previous proteomics studies, we demonstrated that H2O2 stimulates oxidative post-translational modifications on class II Poly(A) binding proteins (PABPs). We hypothesized that these affect RNA binding activity. To address redox regulation of these abiotic stress-related PABPs, we generated transgenic plants in which wildtype and Cys-mutated PABPs are expressed and which will be subjected to detailed phenotypic and biochemical analyses.