Code
3F015211
Duration
01 October 2011 → 30 September 2014
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Promotor
Fellow
Research disciplines
-
Medical and health sciences
- Endocrinology and metabolic diseases
- Orthopaedics
- Endocrinology and metabolic diseases
- Orthopaedics
- Endocrinology and metabolic diseases
- Orthopaedics
Keywords
sex steroids
bone
body composition
gender identity disorder
Project description
Context
Therapy of gender identity disorder induces an altered hormonal milieu.
Design
Prospective intervention study in 100 transsexuals,
cross-sectional study after long-term therapy in 50 female-to-male transsexuals
Objective
To explore the interplay of bone, fat, steroids and metabolism in relation to cross-sex hormonal therapy
Methods
Body composition and bone imaging, serum/tissue hormones, muscle/fat biopsies and mRNA expression of regulating factors