Every day we reconstruct parts of the body that have been removed or are missing for traumatic, oncological or congenital reasons. While today this is done by autologous transplantation, in the future we want to repair these tissues by locally influencing the surrounding tissues or by building autologous tissues in bioreactors.

With tissue regeneration we intend to influence the loco-regional ecosystem of cells (of the host) together with its secretome (inter-cellular communication). We study the best way to add cells in loco and have them survive. Exosome modifications and supplementation are additional alternatives.

Organ bioprinting is building 3D structures from living cells. Research focuses on the microbiology of precursor cells (stem cells), their interaction with each other (communication), angiogenesis, their environment and the intercellular matrix (solid or liquid). Tissue inflammation and oncological risks are also studied.