The Kenya Vision 2030, the National Water Policy 2021 and the United Nations SDG 6 all aim at improved access to affordable clean drinking water especially for the most vulnerable people. This is, however, greatly impeded by severe pollution of water resources. To contribute to the long-term desired change, this project defines 5 action points: (i) research and educational capacity building with a key role for staff members and postgraduate students, (ii) comprehensive monitoring of conventional and emerging water contaminants in Kenya’s surface water and boreholes, (iii) examining levels and risk of antimicrobial resistance, (iv) a point-of-use water treatment device, and (v) engagement of local communities and multiple stakeholders.