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Project

A human pluripotent stem cell derived differentiation model for the study of normal and transformed sympathoadrenal progenitors

Information

Project Team

Outputs and Outcomes

Publications

Human iPSC modeling recapitulates in vivo sympathoadrenal development and reveals an aberrant developmental subpopulation in familial neuroblastoma

Stéphane Van HaverYujie FanSarah-Lee BekaertCeline EveraertWouter Van LoockeVittorio ZanzaniJoke DeschildreInes Fernandez MaestreAdrianna AmaroVanessa VermeirssenKatleen De PreterTing ZhouAlex KentsisLorenz StuderFranki SpelemanStephen S. Roberts et al.

A1 Journal Article in ISCIENCE

2024

SOX11 regulates SWI/SNF complex components as member of the adrenergic neuroblastoma core regulatory circuitry

Bieke DecaestekerAmber LouwagieSiebe LoontiensFanny De VloedSarah-Lee BekaertJuliette RoelsSuzanne VanhauwaertSara De BrouwerEllen SandersA BerezovskayaGeertrui DeneckerEva D'haeneStéphane Van HaverWouter Van LoockeJo Van DorpeDavid CreytensNadine Van RoyTim PietersChristophe Van NesteM FischerPieter Van VlierbergheSS RobertsJ SchulteS EkR VersteegJ KosterJ van NesM ZimmermanKatleen De PreterFranki Speleman et al.

A1 Journal Article in NATURE COMMUNICATIONS

2023