Project

Determining the role and mode of cell death in Necrotizing Enterocolitis

Duration
01 October 2015 → 31 October 2018
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Other biological sciences
  • Medical and health sciences
    • Gastro-enterology and hepatology
    • Immunology
    • Laboratory medicine
    • Palliative care and end-of-life care
    • Regenerative medicine
    • Other basic sciences
    • Gastro-enterology and hepatology
    • Immunology
    • Laboratory medicine
    • Palliative care and end-of-life care
    • Regenerative medicine
    • Other clinical sciences
    • Other health sciences
    • Nursing
    • Other paramedical sciences
    • Gastro-enterology and hepatology
    • Immunology
    • Laboratory medicine
    • Palliative care and end-of-life care
    • Regenerative medicine
    • Other translational sciences
    • Other medical and health sciences
Keywords
Necrotizing enterocolitis cell death intestinal inflammation
 
Project description

Necrotizing enterocolitis (NEC) is an intestinal inflammatory disease of newborns that rapidly progresses to deep mucosal necrosis. Its pathogenesis is still unclear. We hypothesize, that cell death of the outer layer of the intestine is the initiating cause of NEC. Therefore, we aim to identify which cell death pathways act as a key player in this disease.