Project

Influence of methylamines on Escherichia coli viability

Duration
02 August 2012 → 06 September 2013
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Animal biology
    • Biochemistry and metabolism
    • Microbiology
    • Systems biology
  • Medical and health sciences
    • Laboratory medicine
    • Medical biochemistry and metabolism
    • Microbiology
    • Laboratory medicine
    • Medical biochemistry and metabolism
    • Laboratory medicine
    • Medical biochemistry and metabolism
    • Microbiology
  • Agricultural and food sciences
    • Veterinary medicine
    • Other veterinary sciences
    • Other agricultural, veterinary and food sciences
Keywords
enterotoxigenic Escherichia coli flow cytometry viability methylamines
 
Project description

A screeningmodel, based on flow cytometric and other techniques, was developed to assess the influence of methylamines on the viability of enterotoxigenic Escherichia coli. Results show a decrease of ETEC viability after exposure to glycine, sarcosine and imethylglycine, but not betaine, under alkaline conditions (pH 9,0-10,0), due to a disturbance of bacterial pH homeostasis mechanisms.