Research Explorer

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Project

Development of a novel assay to characterize the HIV-1 reservoir using long-read sequencing

Outputs & Impact

Publications & research data ( 7 )

Blood and tissue HIV-1 reservoirs display plasticity and lack of compartmentalization in virally suppressed people

Marion PardonsLaurens LambrechtsYtse NoppeLiesbet TermoteSofie De BraekeleerJerel VegaEllen Van GulckSarah GerloLinos Vandekerckhove

A1 Journal Article in NATURE COMMUNICATIONS

Integrative assessment of total and intact HIV-1 reservoir by a 5-region multiplexed rainbow DNA digital PCR assay

Mareva DelporteLaurens LambrechtsEvy BlommeWillem van SnippenbergSofie RutsaertMaxime VerschooreEvelien De SmetYtse NoppeNele De LangheMarie-Angélique De Scheerder et al.

A1 Journal Article in CLINICAL CHEMISTRY

Potent latency reversal by Tat RNA-containing nanoparticle enables multi-omic analysis of the HIV-1 reservoir

Marion PardonsBasiel ColeLaurens LambrechtsWillem van SnippenbergSofie RutsaertYtse NoppeNele De LangheAnnemieke DhondtJerel VegaFilmon Eyassu et al.

A1 Journal Article in NATURE COMMUNICATIONS

HIV-PULSE : a long-read sequencing assay for high-throughput near full-length HIV-1 proviral genome characterization

Laurens LambrechtsNoah BonineRita VerstraetenMarion PardonsYtse NoppeSofie RutsaertFilip Van NieuwerburghWim Van CriekingeBasiel ColeLinos Vandekerckhove

A1 Journal Article in NUCLEIC ACIDS RESEARCH

HIV-PULSE : a long-read sequencing assay for high-throughput near full-length HIV-1 proviral genome characterization

Laurens LambrechtsNoah BonineRita VerstraetenMarion PardonsYtse NoppeSofie RutsaertFilip Van NieuwerburghWim Van CriekingeBasiel ColeLinos Vandekerckhove

Extensive characterization of HIV-1 reservoirs reveals links to plasma viremia before and during analytical treatment interruption

Basiel ColeLaurens LambrechtsZoe BoyerYtse NoppeMarie-Angélique De ScheerderJohn-Sebastian EdenBram VranckenTimothy E. SchlubSherry McLaughlinLisa M. Frenkel et al.

A1 Journal Article in CELL REPORTS

Organ-specific genome diversity of replication-competent SARS-CoV-2

Jolien Van CleemputWillem van SnippenbergLaurens LambrechtsAmélie DendoovenValentino D'OnofrioLiesbeth CouckWim TrypsteenJan VanrusseltSebastiaan TheunsNick Vereecke et al.

A1 Journal Article in NATURE COMMUNICATIONS

Activities ( 0 )

Results

Impact narratives ( 0 )

Patents ( 0 )