Research Explorer

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Project

Engineering of chimeric bacteriophage-derived endolysins and selection of staphylolytic and streptolytic candidates for the treatment of Gram-positive mammary gland infections in cows.

Outputs and Outcomes

Publications

Endolysin NC5 improves early cloxacillin treatment in a mouse model of Streptococcus uberis mastitis

Niels Vander ElstJulie BellemansRob LavigneYves BriersEvelyne Meyer

A1 Journal Article in APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Development of engineered endolysins with in vitro intracellular activity against streptococcal bovine mastitis‐causing pathogens

Niels Vander ElstJoni BertHerman FavoreelRob LavigneEvelyne MeyerYves Briers

A1 Journal Article in MICROBIAL BIOTECHNOLOGY

Engineering of bacteriophage-derived endolysins to treat streptococcal mammary gland infections

Niels Vander ElstEvelyne MeyerYves BriersRob Lavigne

Endolysin NC5 improves early cloxacillin treatment in a mouse model for bovine Streptococcus uberis mastitis

Julie BellemansNiels Vander ElstRob LavigneYves BriersEvelyne Meyer

A method for the purification of non-pyrogenic bacteriophage derived endolysins with an in vitro or in vivo application

Niels Vander ElstVincent De MaesschalckPhilippe De GrooteEvelyne MeyerRob LavigneYves Briers