Research Explorer

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Project

The role of miRNA expression in normal and malignant T-cel development

Outputs and Outcomes

Code

3G020209

Duration

01 January 2009 → 31 December 2014

Funding

Research Foundation - Flanders (FWO)

Promotor

Franki Speleman

Research disciplines

Natural sciences
- Genetics
- Systems biology
Medical and health sciences
- Molecular and cell biology
- Morphological sciences
- Oncology
- Morphological sciences
- Oncology
- Molecular and cell biology
- Morphological sciences
- Oncology

Keywords

T-ALL microRNA genetics

Project description

T-ALL is an aggressive blood cancer with a poor prognosis. In this project we want to identify miRNAs and miRNA target genes who contribute to the pathogenesis of T-ALL. Novel insights in this additional level of gene regulation can possibly lead to new therapeutical opportunities in T-ALL and certain miRNA signatures can possibly function as molecular biomarkers for prognosis of T-ALL.

English

Dutch

English

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