Project

Isotopic analysis of Cu, Fe and Zn in whole blood, serum and cerebrospinal fluid via multi-collector ICP - mass spectrometry: a novel approach to obtain insight into metabolism and to diagnose metal-related diseases

Duration
01 October 2014 → 30 September 2020
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Instrumental methods
    • Inorganic elements and compounds
  • Medical and health sciences
    • General diagnostics
Keywords
cerebrospinal fluid isotopic analysis multi-collector ICP-mass spectrometry transition metals Cu Fe Zn whole blood serum
 
Project description

The isotopic composition of Cu, Fe and Zn will be determined in whole blood, serum and cerebrospinal fluid via multi-collector ICP-mass spectrometry. Novel and improved analytical methods will be developed for this purpose. The capabiities of this approach for i) providing an enhanced insight into the metabolism of these transition metals and ii) diagnosis of diseases will be evaluated.