Cereulide, beauvericin and enniatins are selected because of their emerging character, public health relevance, extreme stability, omnipresence of respective microorganisms, possible accumulation in the body, and similarity in the chemical nature (cyclodepsipetides). Quantification and characterization of toxic effects will provide information necessary for proper prevention and intervention in human health protection. For this purpose novel biosensors with different cell cultures will be used in the current proposal.