Within the adsorption section of the INCAT-research group, it is investigated which separation technique(s) (adsorption, ion exchange, distillation, extraction, crystallization, …) can be used for separating and recovering high-value chemicals (such as hydroxycinnamic acids, vanillin, …) from a biomass stream. The first step in choosing an appropriate separation technique is to map the phase equilibria, where the relevant phases can be gas, liquid, and solid. This is studied both experimentally and theoretically, initially on model streams. Once the appropriate separation technique(s) have been chosen, these techniques are designed and simulated, and subsequently experimentally validated with the actual streams. Criteria include yield and purity of the obtained valuable streams, as well as the stability of the respective separation processes. Finally, a techno-economic analysis of the proposed separation processes is performed.