Project

Study of the molecular pathogenesis of the Ehlers-Danlos syndrome

Duration
01 January 2012 → 31 December 2014
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Genetics
    • Systems biology
  • Medical and health sciences
    • Dermatology
    • Molecular and cell biology
    • Orthopaedics
    • Dermatology
    • Orthopaedics
    • Dermatology
    • Molecular and cell biology
    • Orthopaedics
Keywords
brittle cornea syndrome genome technology ehlers-Danlos syndrome ZNF469
 
Project description

In this project a combination of biochemical and molecular techniques will be used to unravel the molecular basis and pathogenesis of several EDS subtypes. In particular the role of ZNF469 in the pathogenesis of EDS6 related phenotypes and its putative functional role in connective tissue biology will be explored.