Code
3E007509
Duration
01 October 2009 → 13 February 2016
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Promotor
Fellow
Research disciplines
-
Natural sciences
- Genetics
- Systems biology
-
Medical and health sciences
- Molecular and cell biology
- Molecular and cell biology
Project description
Abstract (max. 60 woorden): IgE plays a central role in allergy by activating mast cells and facilitating allergen presentation to Th2 lympghocytes. Accumulating evidence suggests that IgA plays a protective role in allergy by antagonizing the effects of IgE. Therefore using three proven IgA promoting regimens: IL-21+TGFB1, cholera toxin B (CTB) and Lactococci engineerd to express allergen and CTB