Project

The formation of metastases is the main cause of cancer-related mortality

Duration
01 October 2012 → 30 September 2018
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Organic chemistry
  • Medical and health sciences
    • Morphological sciences
    • Oncology
    • Morphological sciences
    • Oncology
    • Biomarker discovery and evaluation
    • Drug discovery and development
    • Medicinal products
    • Pharmaceutics
    • Pharmacognosy and phytochemistry
    • Pharmacology
    • Pharmacotherapy
    • Toxicology and toxinology
    • Other pharmaceutical sciences
    • Morphological sciences
    • Oncology
Keywords
drug design metastasis cancer
 
Project description

The formation of metastases is the main cause of cancer-related mortality (90%). Strikingly, no effective anti-metastatic therapy is available in the clinic yet. N-Cadherin (NCad) is a protein that is abnormally active in metastatic tumors and helps them spread. The current project aims at developing molecules which can block NCad in patients.