The BCCM/LMBP activities are continuously supported by the research activities of its host laboratory, which focus on molecular and cellular mechanisms that are at the origin of chronic inflammation, autoimmune diseases, infectious diseases and cancer. These mechanisms are mainly studied in cellular and animal model systems by using the most advanced methods of molecular biology, cell biology and immunology. Expression plasmids for human and mouse genes are frequently generated and extensively used, offering an ideal environment for BCCM/LMBP. Research of the host laboratory is multidisciplinary with molecular biologists, immunologists, cell biologists, and bioinformaticians collaborating with clinicians. It is the ambition of the host laboratory to translate basic research into innovative ways for diagnosis and therapy of human diseases.