The main research goal is the development of microbial management plans for diverse contaminants present in the environment. There are approximately 4,500 toxic chemicals, including PCBs (Polychlorinated Biphenyls), pesticides, furans, dioxins, and phenols, which fall under the category of persistent organic pollutants (POPs). To maintain a healthy environment clean-up of these contaminants is of crucial importance. This can only be achieved by developing an innovative monitoring strategy and clean-up technology. This research aims to develop smart strategies for both purposes by employing an interdisciplinary approach. Our proposed research will focus on studying the local and complex microbiome at contaminated sites.