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Medical and health sciences
- Molecular diagnostics
The purpose of our project is the analysis and improvement of current care (diagnosis, treatment and follow-up) for patients with a bone or soft tissue tumor.
Anatomopathological studies (histomorphology, immunohistochemical and molecular genetic data) and real-life data (clinical presentation and clinical follow-up; medical imaging) of patients who were discussed, examined and treated by our multidisciplinary tumor working group bone and soft tissue tumors UZ Ghent in the period 2000 – 2024 will be analyzed in detail: which (clinical, histopathological, radiological) characteristics predict the risk of local recurrence (e.g. atypical lipomatous tumors/liposarcomas, giant cell tumors, solitary fibrous tumors) and which characteristics predict a good chance of survival (response to therapy) (e.g. osteosarcomas, Ewing sarcomas). For each patient, we will provide a coupling with sample collection for scientific projects, as well as the prospective biobank collection. This will allow us to test traceability of samples and conduct a planned translational scientific project.
A benchmarking exercise with the Karolinska institute will also be set up using existing indicators.