Acronym
METAL
Code
F2024/IOF-StarTT/008
Duration
15 April 2024 → 14 April 2026
Funding
Regional and community funding: Industrial Research Fund
Promotor
Research disciplines
-
Medical and health sciences
- Development of bioinformatics software, tools and databases
- Cancer biology
- Cancer therapy
Keywords
metastasis
New Approach Method (NAM)
phenotypic assay
Project description
We present a ’New Approach Method‘ (NAM) which mimics dissemination, dormancy and colonization of cancer cells all within a one-step phenotypic assay. This METAstasis in the Lab (‘METAL’) assay does not require animals and allows to intervene in each step of the metastatic cascade. Development of image processing software and further validation of the assay will enable evaluation of therapeutic drug.