Thetaburst stimulation, research investigating the mechanism of action and neuroplascticity in both normal volunteers and patients with neuropsychiatric disorders

01 June 2015 → 31 May 2017
Regional and community funding: Special Research Fund
Research disciplines
  • Medical and health sciences
    • Neurophysiology
    • Psychotherapy
    • Neurophysiology
    • Psychotherapy
    • Neurophysiology
    • Psychotherapy
  • Engineering and technology
    • Biomedical image processing
    • Biomedical instrumentation
    • Biomedical signal processing
neuroplasticity TMS TBS thetaburst stimulation neuromodulation transcranial magnetic stimulation cortical excitability
Project description

TBS is a novel type of the non-invasive TMS technique with pre-clinical evidence for inducing stonger neuroplasticity compared to standard protocols. The mechanism of action of TBS will be investigated using stateof-the-art functional and anatomic neuroimaging and neurofysiological recordings. By investigating the mechanism of action and effects of TBS on cortical excitability in normal volunteers, pilot trials can be performed in patients with refractory neuropscyhiatric disorders such as epilepsy, depression, obsessive compulsive disorder where neuromodulatory effects are required to intervene with pathological brain networks.