Research Explorer

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Project

In the moonlight of GTF3A: a new way to see innate antiviral signaling?

Outputs & Impact

Publications & research data ( 6 )

Inborn errors of nucleic acid sensing and type I interferon signaling determine viral susceptibility in humans

Leslie NaesensSteven CallensTessa KerreSimon TavernierFilomeen Haerynck

A1 Journal Article in EUROPEAN JOURNAL OF IMMUNOLOGY

The RNA polymerase III–RIG-I axis in antiviral immunity and inflammation

Leslie NaesensFilomeen HaerynckMichaela U. Gack

A1 Journal Article in TRENDS IN IMMUNOLOGY

GTF3A mutations predispose to herpes simplex encephalitis by disrupting biogenesis of the host-derived RIG-I ligand RNA5SP141

Leslie NaesensSantoshi MuppalaDhiraj AcharyaJosephine NemegeerDelfien BogaertJung-Hyun LeeKatrien StaesVeronique DebackerPieter De BleserMarieke De Bruyne et al.

A1 Journal Article in SCIENCE IMMUNOLOGY

Shortcutting the diagnostic odyssey : the multidisciplinary program for undiagnosed rare diseases in adults (UD-PrOZA)

Nika SchuermansDimitri HemelsoetWim TerrynSanne SteyaertRudy Van CosterPaul CouckeWouter SteyaertBert CallewaertElke BogaertPATRICK VERLOO et al.

A1 Journal Article in ORPHANET JOURNAL OF RARE DISEASES

Mutations in RNU7-1 weaken secondary RNA structure, induce MCP-1 and CXCL10 in CSF, and result in Aicardi-Goutières syndrome with severe end-organ involvement

Leslie NaesensJosephine NemegeerFilip RoelensLore VallaeysMarije MeuwissenKatrien JanssensPatrick VerlooBenson OgunjimiDimitri HemelsoetLevi Hoste et al.

A1 Journal Article in JOURNAL OF CLINICAL IMMUNOLOGY

TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C

Levi HosteLisa RoelsLeslie NaesensVictor BosteelsStijn VanheeSam DupontCedric BosteelsRobin BrowaeysNiels VandammeKevin Verstaen et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

Activities ( 0 )

Results

Impact narratives ( 0 )

Patents ( 0 )