Research Explorer

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Project

In the moonlight of GTF3A: a new way to see innate antiviral signaling?

Outputs and Outcomes

Publications

The RNA polymerase III–RIG-I axis in antiviral immunity and inflammation

Leslie NaesensFilomeen HaerynckMichaela U. Gack

A1 Journal Article in TRENDS IN IMMUNOLOGY

GTF3A mutations predispose to herpes simplex encephalitis by disrupting biogenesis of the host-derived RIG-I ligand RNA5SP141

Leslie NaesensSantoshi MuppalaDhiraj AcharyaJosephine NemegeerDelfien BogaertJung-Hyun LeeKatrien StaesVeronique DebackerPieter De BleserMarieke De BruyneElfride De BaereMichiel van GentGuanQun LiuBart LambrechtJens StaalTessa KerreRudi BeyaertJonathan MaelfaitSimon TavernierMichaela U. GackFilomeen Haerynck et al.

A1 Journal Article in SCIENCE IMMUNOLOGY

Shortcutting the diagnostic odyssey : the multidisciplinary program for undiagnosed rare diseases in adults (UD-PrOZA)

Nika SchuermansDimitri HemelsoetWim TerrynSanne SteyaertRudy Van CosterPaul CouckeWouter SteyaertBert CallewaertElke BogaertPatrick VerlooArnaud VanlanderElke DebackereJody GhijselsPontus LeBlancHannah VerdinLeslie NaesensFilomeen HaerynckSteven CallensBart DermautBruce PoppeJan De BleeckerPatrick SantensPaul BoonGuy LaureysTessa Kerre[missing] for UD-PrOZA et al.

A1 Journal Article in ORPHANET JOURNAL OF RARE DISEASES

Mutations in RNU7-1 weaken secondary RNA structure, induce MCP-1 and CXCL10 in CSF, and result in Aicardi-Goutières syndrome with severe end-organ involvement

Leslie NaesensJosephine NemegeerFilip RoelensLore VallaeysMarije MeuwissenKatrien JanssensPatrick VerlooBenson OgunjimiDimitri HemelsoetLevi HosteLisa RoelsMarieke De BruyneElfride De BaereJo Van DorpeAmélie DendoovenAnne SiebenGillian I. RiceTessa KerreRudi BeyaertCarolina UggentiYanick J. CrowSimon TavernierJonathan MaelfaitFilomeen Haerynck[missing] Program for Undiagnosed Rare Diseases (UD-PrOZA) et al.

A1 Journal Article in JOURNAL OF CLINICAL IMMUNOLOGY

TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C

Levi HosteLisa RoelsLeslie NaesensVictor BosteelsStijn VanheeSam DupontCedric BosteelsRobin BrowaeysNiels VandammeKevin VerstaenJana RoelsKarel Van DammeBastiaan MaesElisabeth De LeeuwJozefien DeclercqHelena Catharine AegerterLeen SeysUrsula SmoleSofie De PrijckManon VanheerswynghelsKarlien ClaesVeronique DebackerGert Van IsterdaelLynn BackersKathleen ClaesPaul BastardEmmanuelle JouanguyShen-Ying ZhangGilles MetsJoke DehoorneKristof VandekerckhovePetra SchelstraeteJef WillemsPatrick StordeurSophie JanssensRudi BeyaertYvan SaeysJean-Laurent CasanovaBart LambrechtFilomeen HaerynckSimon TavernierHeidi Schaballie[ missing ] MIS-C Clinicians et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE