Powerful methods for detecting gene-gene interactions

01 January 2007 → 31 October 2009
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Applied mathematics in specific fields
    • Statistics and numerical methods
    • Genetics
    • Systems biology
  • Medical and health sciences
    • Molecular and cell biology
    • Molecular and cell biology
genetic association studies statistical genetics multiple testing
Project description

This project aims to develop powerful statistical methods for detecting gene-gene interactions, in particular (1) a general strategy for minimizing the risk of Type I en II errors in genomewide detection of gene-gene interactions, and (2) specific statistical tests for gene-gene interaction based on microarray data and family-based designs.