Code
01W02610
Duration
01 October 2010 → 30 September 2012
Funding
Regional and community funding: Special Research Fund
Promotor
Research disciplines
-
Natural sciences
- Other chemical sciences
- Biochemistry and metabolism
- Plant biology
- Systems biology
-
Medical and health sciences
- Medical biochemistry and metabolism
- Medical biochemistry and metabolism
- Nutrition and dietetics
- Medical biochemistry and metabolism
-
Agricultural and food sciences
- Agricultural animal production
- Agricultural plant production
- Food sciences and (bio)technology
- Horticultural production
Keywords
rat
insect model
bioactive peptides
in vitro
satiety
cholecystokinin
in vivo
receptor
Project description
This project evaluates the use of insects as model to investigate the potential of bioactive peptides to reduce food intake by interacting with the cholecystokinin-receptor. After enzymatich hydrolysis of food proteins, bioactive peptides are isolated and their activity on the cholecystokinin-receptor is determined using the selected insect models. Moreover, their in vivo satiating effect in rats as model for human.