Research Explorer

Project

The role of the microbiome and host-pathogen interactions in the development of placentitis
Code
01D17422
Duration
01 January 2023 → 30 June 2025
Funding
Regional and community funding: Special Research Fund
Promotor-spokesperson
Research disciplines
  • Natural sciences
    • Bioinformatics of disease
    • Infectious diseases
    • Microbiomes
  • Agricultural and food sciences
    • Veterinary reproduction and obstetrics
Keywords
Pregnancy abortion placentitis microbiome host-pathogen interaction dual-RNA sequencing
 
Project description
 

To better understand the pathophysiology of placentitis, we will characterize the microbiome in healthy and diseased placentae and elucidate the interactions between host, microbiome, and pathogen(s). The results will give insight in the mechanisms used by the pathogen to colonize the host tissue and the activation of the defence mechanisms of the host to overcome the infection.