Code
01P14010
Duration
01 October 2010 → 30 November 2014
Funding
Regional and community funding: Special Research Fund
Promotor
Fellow
Research disciplines
-
Natural sciences
- Systems biology
-
Medical and health sciences
- Hematology
- Laboratory medicine
- Medical systems biology
- Morphological sciences
- Oncology
- Hematology
- Laboratory medicine
- Medical systems biology
- Molecular and cell biology
- Morphological sciences
- Oncology
- Hematology
- Laboratory medicine
- Medical systems biology
- Molecular and cell biology
- Morphological sciences
- Oncology
Keywords
T-ALL
T-cells
PHF6
leukemia
Project description
T-ALL results from malignant transformation of thymocytes. Although treatment outcome has improved, many factors contributing to T-ALL development remain unknown. Recently, PHF6 was identified as a novel tumor suppressor gene in the pathogenesis of T-ALL at our lab. The aim of this project is to investigate the cellular function of PHF6 and its role in normal T-cell and T-ALL development