Molecular detection of multidrug resistance in Mycobacterium tuberculosis from slides and filter paper cards in middle and low-income countries

01 January 2013 → 31 December 2015
Funding by bilateral agreement (private and foundations)
Research disciplines
  • Natural sciences
    • Systems biology
  • Medical and health sciences
    • Biophysics
    • Biophysics
    • Biophysics
mycobacteria drug-resistance tuberculosis
Project description

Difficulties with drug resistance detection are often caused by the limitation of transport of samples. The main objective of this project is to investigate the feasibility to use DNA extracted from different transportation supports (sputum smear-slides, filter paper cards, and ethanol-stored samples) for the molecular detection of rifampicin and isoniazid resistance using the GenoType MTBDRplus kit.