Project

Synthesis of natural product scaffolds via intramolecular cationic cascade cyclisations

Code
01CD12123
Duration
01 January 2024 → 30 June 2024
Funding
Regional and community funding: Special Research Fund
Promotor
Research disciplines
  • Natural sciences
    • Organic chemical synthesis
Keywords
Cascade reactions Carbocations Natural product
 
Project description
Terpenoids are a structurally and functionally diverse category of biologically active metabolites. Most share a complex carbocyclic framework which is considered a privileged scaffold for drug discovery. This research aims to form these challenging scaffolds from their linear precursors in a one-step cationic cascade reaction.