Research Explorer

Project

Synthesis of triazole analogues of Peloruside A via “click”-chemistry as potential antitumor compounds.
Code
01D27914
Duration
01 November 2014 → 31 October 2018
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Inorganic chemistry
    • Organic chemistry
    • Theoretical and computational chemistry
    • Other chemical sciences
  • Engineering and technology
    • Chemical product design and formulation
    • Biomaterials engineering
Keywords
peloruside A antitumor
 
Project description

The aim of this project is the synthesis of simplified analogues of Peloruside A. This should lead to a better understanding of the way of action and of which pharmacophoric groups are responsible for its antitumor activity. This should also result in analogues which are synthetically more easily accessible.