Project

Characterizing the in vivo importance of OTULIN through mouse gene targeting studies

Code
01D25618
Duration
01 October 2018 → 01 November 2019
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Medical and health sciences
    • Gastro-enterology and hepatology
    • Immunology
    • Physiology
    • Gastro-enterology and hepatology
    • Immunology
    • Physiology
    • Gastro-enterology and hepatology
    • Immunology
    • Physiology
Keywords
Inflammation NF-kB OTULIN
 
Project description

This project will investigate the role of OTULIN in inflammatory signaling and pathology. For this I will make use of unique conditional OTULIN knockout mice in order to identify the physiological importance of OTULIN in intestinal and liver homeostasis and inflammatory pathology.