Research Explorer

Project

Ceation of patient specific stem cells through somatic cell nuclear transfer of induced pluripotent stem cells
Code
3G062910
Duration
01 January 2010 → 31 December 2015
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Genetics
  • Medical and health sciences
    • Endocrinology and metabolic diseases
    • Gynaecology and obstetrics
    • Molecular and cell biology
    • Morphological sciences
    • Endocrinology and metabolic diseases
    • Gynaecology and obstetrics
    • Molecular and cell biology
    • Morphological sciences
    • Nursing
    • Endocrinology and metabolic diseases
    • Gynaecology and obstetrics
    • Molecular and cell biology
    • Morphological sciences
Keywords
pluripotency stem cells nuclear transfer
 
Project description
 

Somatic cell nuclear transfer and parthenogenesis involve two major strategies to produce patient specific pluripotent stem cells. The key steps in this technology (enucleation artificial activation) need further optimisation in human. In parallel, we will ivestigate whether induced pluripotent stem cells have similar characteristics and capacities as human embryonic stem cells by intensive molecular comparsion.