Code
3G018711
Duration
01 January 2011 → 31 December 2014
Funding
Research Foundation - Flanders (FWO)
Promotor
Research disciplines
-
Medical and health sciences
- Biomarker discovery and evaluation
- Drug discovery and development
- Medicinal products
- Pharmaceutics
- Pharmacognosy and phytochemistry
- Pharmacology
- Pharmacotherapy
- Toxicology and toxinology
- Other pharmaceutical sciences
Keywords
doxorubicin
ultrasound
microbubbles
metastasis
Project description
This project evaluates the use of doxorubicin-loaded microbubbles (i.e.: ultrasound responsive gas bubbles) for the destruction of circulating tumor cells. A new type of microbubbles will be designed for this purpose. These microbubbles have a surface loaded with anti-N-Cadherin antibodies that will be used to specifically recognize the circulating metastasis.