Code
3G032113
Duration
01 January 2013 → 31 December 2018
Funding
Research Foundation - Flanders (FWO)
Promotor
Research disciplines
-
Natural sciences
- Biochemistry and metabolism not elsewhere classified
- Synthetic biology
-
Engineering and technology
- Industrial microbiology
Keywords
metabolic engineering
fine tuning expression
synthetic biology
escherichia coli
Project description
Transfer of multi-gene or poorly understood heterologous pathways into the production host leads to imbalances. Hence, fine tuning the expression of these pathways in specific conditions is mandatory for the succesfull production. This proposal aims to fill the technological and knowledge gap by providing novel metabolic engineering tools allowing fine tuning of complex pathways to enhance production of toxic molecules.