Code
01D22215
Looptijd
01-10-2015 → 30-09-2019
Financiering
Regional and community funding: Special Research Fund
Promotor
Fellow
Onderzoeksdisciplines
-
Engineering and technology
- Biocatalysis and enzyme technology
- Bioprocessing, bioproduction and bioproducts
- Fermentation
- Industrial microbiology
- Industrial biotechnology not elsewhere classified
Trefwoorden
Glycobiotechnologie
Complexe glycanen
Lipopolysaccharides
Projectomschrijving
The synthesis of complex glycans such as human milk oligosaccharides, which ameliorate infant nutrition, and glycoproteins, important for carbohydrate-vaccines development, requires a new biotechnological production platform. In this project a platform technology will be created that eliminates unwanted glycosylations stemming from the production host’s inherent glycosylation metabolism and modifies the host’s lipopolysaccharide structure to eliminate its endotoxin activity.