Research Explorer

Project

From gene to aortic dissection - detailed study of the etiology and pathogenesis and of cardiovascular characteristics of inheritable thoracic aortic aneurysms and dissections
Code
01J10213
Duration
01 March 2013 → 31 October 2018
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Genetics
    • Systems biology
  • Medical and health sciences
    • Molecular and cell biology
    • Molecular and cell biology
Keywords
thoracic aortic aneurysm gene expression proteomics TGFbeta pathway
 
Project description

Aortic aneurysms are associated with significant morbidity and mortality. Study of genetic causes of aortic aneurysms allows us to gain better insights into the underlying pathogenesis and may offer new targets for optimizing treatment. With this project, we aim to search for new genes and gain better insights into the moecualr pathways of aneurysm formation.