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Project

Exploiting the methylerythritol phosphate pathway as a source of drug targets for novel anti-infectives

Information

Project Team

Organisations

Outputs and Outcomes

Publications

Studying target-engagement of anti-infectives by solvent-induced protein precipitation and quantitative mass spectrometry

Lorenzo BizzarriDominik SteinbrunnThibaut QuennessonAntoine LacourGabriella Ines BianchinoPatricia BravoPhilippe ChaignonJonas LohsePascal MäserMyriam SeemannSerge Van CalenberghAnna K. H. HirschHannes Hahne et al.

A1 Journal Article in ACS INFECTIOUS DISEASES

2024

3D-printed wound dressings containing a fosmidomycin-derivative prevent Acinetobacter baumannii biofilm formation

Frits van CharanteDavid Martínez-PérezClara Guarch-PérezCharlotte CourtensAndrea SassEmilia ChoińskaJoanna IdaszekSerge Van CalenberghMartijn RioolSebastian A. J. ZaatWojciech ŚwięszkowskiTom Coenye et al.

A1 Journal Article in ISCIENCE

2023

Acyloxymethyl and alkoxycarbonyloxymethyl prodrugs of a fosmidomycin surrogate as antimalarial and antibacterial agents

Charlotte CourtensFrits van CharanteThibaut QuennessonMartijn RisseeuwPaul CosGuy CaljonTom CoenyeSerge Van Calenbergh

A1 Journal Article in EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

2023