Code
01N02112
Duration
01 January 2012 → 31 December 2016
Funding
Regional and community funding: Special Research Fund
Promotor
Research disciplines
-
Medical and health sciences
- Biomarker discovery and evaluation
- Drug discovery and development
- Medicinal products
- Pharmaceutics
- Pharmacognosy and phytochemistry
- Pharmacology
- Pharmacotherapy
- Toxicology and toxinology
- Other pharmaceutical sciences
Keywords
PBPK-modelling
pharmacokinetics
paediatric drug development
Project description
This project aims to evaluate the usefulness of Physiologically Based Pharmacokinetic (PBKP) - Modelling in predicting the pharmacokinetics of drugs en paediatric populations. Current knowledge on PBPK-modelling in children will be expanded, an the resulting model will be tested and validated using the model drugs tramadol and propofol.